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Wet AMD

Eye with Wet Age Related Macular DegenerationWet AMD, also known as CNV, occurs when blood vessels grow and penetrate the retina, leaking blood and fluid that damages your photoreceptor cells.  It is this damage that causes vision loss.

While dry AMD progresses slowly and often causes no vision loss, wet AMD progresses very rapidly.  If left undetected and untreated, the development of wet AMD can lead to blindness in just a matter of months.

Wet AMD or CNV

Retinal View of Wet AMD, or Choroidal Neovascularization

Symptoms of wet AMD include distortions or blind spots in your central visual field.


Metamorphospsia
Scotoma

While there is no way to predict who will develop wet AMD, certain individuals are at greater risk. 

  • Individuals who already have wet AMD in one eye
  • Individuals with dry AMD in both eyes
  • Individuals with dry AMD in one eye 

Early detection of wet AMD is critical. 

Clinical results have demonstrated that outcomes are generally better the earlier new treatments for wet AMD are initiated.  In many cases when wet AMD is detected early, the disease progression can be halted.  If treatment can be initiated when the lesion is small and you still have good visual acuity, your potential to maintain good vision is much better.

The most common treatment for wet AMD consists of drugs known as anti-vascular endothelial growth factor (anti-VEGF) agents.  The anti-VEGF products available in the U.S. are Eylea® (Regeneron), Lucentis® (Genentech, Inc.), and Macugen® (Valeant Pharmaceuticals, Inc.).  Avastin® ( Genentech, Inc.) has also been used to treat wet AMD as an off-label use.