ForeseeHome™ - AMD Monitoring Program

THE TECHNOLOGY

PREFERENTIAL HYPERACUITY PERIMETRY

The ForeseeHome™ AMD Monitor uses a patented technology called Preferential Hyperacuity Perimetry (PHP).  Hyperacuity, or Vernier acuity, is the human ability to perceive minute differences in the relative spatial localization of two objects in space (as illustrated below).  Hyperacuity is 10X more sensitive than standard visual acuity.

Hyperacuity Perimetry

Pathological DistortionsDuring a PHP test, stimuli are successively flashed in various locations of the visual field. A typical stimulus consists of a series of dots, the majority of which are aligned with respect to each other. A few dots are misaligned, creating the perception of a wave or distortion in an otherwise straight line. 

The quick flash of the stimuli ensures that the brain doesn’t “complete” or fill in missing information.  The patient's task is to mark the location where the distortion was perceived. When the stimulus is projected on an unhealthy area of the retina, the patient may perceive two or more distortions on the line: one corresponding to the artificial wave and the other corresponding to the patient’s pathological distortion.

According to the preferential looking principle, when presented with several stimuli, the visual attention of a subject is automatically attracted to the more prominent source. Hence, if the pathological distortion is larger than the artificial wave, the patient is likely to ignore the artificial wave and mark only the location of the pathological distortion.

The ForeseeHome test is designed with various amplitudes of artificial distortions that maximally distinguishes between dry AMD patients and newly diagnosed wet AMD. Numerous evaluations have demonstrated the technology’s keen ability to provide early detection of changes occurring within a patient’s vision, often before the patient is even aware. 

CONNECTIVITY

Testing data is automatically transmitted to the Notal Vision Data Monitoring Center (DMC) at the end of each test. The wireless communication technology (or landline phone connection in locations with poor cellular signals) facilitates fast and reliable transmission of data which is then made available to the physician through a secure website. Tests are continuously compared to a normative database threshold and the patient's own baseline. When a statistically significant change of test patterns is detected, the DMC alerts the clinic so that they can schedule a prompt clinical examination with the patient.

ForeseeHome Transmission

In addition to monitoring test scores, the frequency of use is also tracked. To encourage patients to test at an adequate frequency (i.e., one that will allow timely detection), the DMC will contact the patient if no results are received for seven consecutive days.